Motif ID: FOX{C1,C2}.p2

Z-value: 1.744


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXC2hg19_v1_chr16_+_86600856_866008560.192.9e-01Click!
FOXC1hg19_v1_chr6_+_1610680_16106800.125.1e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_64225496 9.099 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chrX_+_138612894 7.780 NM_000133
F9
coagulation factor IX
chr9_-_104198045 7.710 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr14_+_95047758 7.367 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr2_+_74120132 6.940 ACTG2
actin, gamma 2, smooth muscle, enteric
chr2_+_74120092 6.789 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr14_+_95047730 6.379 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_+_74281884 6.216 ALB
albumin
chr12_+_100867550 5.961 NM_001206977
NM_001206978
NM_001206979
NM_005123
NR1H4



nuclear receptor subfamily 1, group H, member 4



chr2_+_189839078 5.116 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_234621637 4.717 NM_019078
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr4_-_100140330 4.614 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr2_+_189839113 4.473 COL3A1
collagen, type III, alpha 1
chr3_-_149095413 4.462 TM4SF1
transmembrane 4 L six family member 1
chr3_-_149095333 4.378 TM4SF1
transmembrane 4 L six family member 1
chr10_+_7745325 4.311 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_234637772 4.195 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr10_+_7745341 4.009 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_+_100867739 3.966 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr2_+_189839132 3.921 COL3A1
collagen, type III, alpha 1
chr8_-_6735438 3.793 NM_005218
DEFB1
defensin, beta 1
chr3_+_133495925 3.784 TF
transferrin
chr2_-_88427535 3.633 NM_001443
FABP1
fatty acid binding protein 1, liver
chr8_+_55528626 3.618 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chrX_+_106163605 3.615 NM_020384
CLDN2
claudin 2
chr14_-_94919085 3.594 NM_001080451
SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr11_+_114167197 3.569 NNMT
nicotinamide N-methyltransferase
chr10_+_7745284 3.565 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr7_-_50628744 3.524 NM_000790
NM_001242886
NM_001242887
NM_001242888
NM_001242889
NM_001242890
DDC





dopa decarboxylase (aromatic L-amino acid decarboxylase)





chr1_+_199996729 3.497 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr1_-_157522151 3.477 NM_001195388
NM_031281
FCRL5

Fc receptor-like 5

chr10_+_7745354 3.331 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_118892363 3.314 NM_006952
UPK1B
uroplakin 1B
chr2_-_216300444 3.302 FN1
fibronectin 1
chr10_+_96698409 3.275 NM_000771
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr3_+_113616317 3.260 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr3_-_149095458 3.211 TM4SF1
transmembrane 4 L six family member 1
chr7_-_99573637 3.150 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr10_+_96522457 3.092 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr2_+_158958381 2.892 NM_173355
UPP2
uridine phosphorylase 2
chr20_-_6034617 2.826 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr10_+_7745229 2.737 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_+_186350543 2.685 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr2_+_102927961 2.668 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr11_-_116693907 2.657 NM_000482
APOA4
apolipoprotein A-IV
chr3_-_42917191 2.656 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr1_-_59043165 2.431 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr2_+_150187028 2.416 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr8_-_86290333 2.390 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr1_-_202129731 2.299 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr5_+_38845962 2.184 NM_003999
OSMR
oncostatin M receptor
chr12_-_9913415 2.159 NM_001781
CD69
CD69 molecule
chr11_+_118175294 2.109 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr11_+_114167168 2.103 NNMT
nicotinamide N-methyltransferase
chr20_+_42984338 2.097 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr1_+_196857143 2.092 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr4_-_84035888 2.072 PLAC8
placenta-specific 8
chr10_-_82049178 2.042 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr7_+_26400503 2.037 NM_001199837
SNX10
sorting nexin 10
chr5_+_35856990 2.026 NM_002185
IL7R
interleukin 7 receptor
chr2_-_188419049 1.999 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr16_+_56995761 1.990 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr4_+_25657434 1.989 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr17_-_16875388 1.972 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr16_+_82068958 1.954 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_-_6462129 1.941 NM_000613
HPX
hemopexin
chr7_-_92848837 1.940 NM_198151
HEPACAM2
HEPACAM family member 2
chr8_+_103563847 1.913 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr19_-_49116693 1.904 NM_017708
FAM83E
family with sequence similarity 83, member E
chr2_-_88285308 1.893 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr20_-_14318200 1.863 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr14_+_88471467 1.852 NM_003608
GPR65
G protein-coupled receptor 65
chr4_-_84035908 1.841 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr8_+_104831415 1.841 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr3_-_164914448 1.814 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr14_+_95047792 1.770 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr3_-_119278402 1.756 NM_005191
CD80
CD80 molecule
chr12_+_47610244 1.627 FAM113B
family with sequence similarity 113, member B
chr3_-_100712248 1.552 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr2_+_121554866 1.547 NM_005270
GLI2
GLI family zinc finger 2
chr10_-_99790346 1.541 CRTAC1
cartilage acidic protein 1
chr17_-_7082654 1.519 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr1_+_159557615 1.515 NM_001639
APCS
amyloid P component, serum
chr2_+_132480063 1.497 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr6_-_159466019 1.469 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr15_-_58306185 1.469 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr3_+_108541544 1.463 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr4_+_159442865 1.462 NM_001253727
NM_001253728
NM_001253729
NM_001253730
NM_001253732
NM_001253733
NM_021634
RXFP1






relaxin/insulin-like family peptide receptor 1






chr21_+_43823970 1.461 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr1_+_163038934 1.457 NM_001113381
RGS4
regulator of G-protein signaling 4
chr14_-_106733392 1.410 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr17_-_48271968 1.393


chr17_-_7082559 1.392 ASGR1
asialoglycoprotein receptor 1
chr20_-_44175995 1.373 NM_001198986
NM_020398
SPINLW1-WFDC6
SPINLW1
SPINLW1-WFDC6 readthrough
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr12_-_24103953 1.363 SOX5
SRY (sex determining region Y)-box 5
chr14_-_94854910 1.361 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_+_39063851 1.361 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr17_-_79623561 1.349 NM_002602
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr14_-_106452693 1.327 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_95298251 1.238 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_+_198608136 1.237 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr11_-_5255712 1.237 NM_000519
HBD
hemoglobin, delta
chr5_+_54320083 1.225 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr12_-_56236614 1.210 NM_002429
MMP19
matrix metallopeptidase 19
chr13_+_96085852 1.207 NM_001160100
NM_182848
CLDN10

claudin 10

chr5_+_140165875 1.206 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr14_-_94855120 1.199 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_110933635 1.196 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr15_-_22473092 1.186


chr21_-_43735462 1.162 TFF3
trefoil factor 3 (intestinal)
chr4_-_48136245 1.159 NM_003328
TXK
TXK tyrosine kinase
chr7_-_106301329 1.159 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr19_+_38810461 1.150 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr17_-_36105005 1.148 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr6_+_122931541 1.136 PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr5_-_35230822 1.135 NM_000949
PRLR
prolactin receptor
chr9_+_97766414 1.128 C9orf3
chromosome 9 open reading frame 3
chr20_-_44168128 1.115 NM_080827
WFDC6
WAP four-disulfide core domain 6
chr3_+_149192479 1.114 TM4SF4
transmembrane 4 L six family member 4
chr7_-_50633042 1.113 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_-_108096693 1.090 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr1_+_201979747 1.073 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_7623038 1.069 NM_020877
DNAH2
dynein, axonemal, heavy chain 2
chr14_+_100531764 1.047 EVL
Enah/Vasp-like
chr7_-_98805088 1.036 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr12_+_52306112 1.035 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr3_-_116164363 1.032 NM_002338
LSAMP
limbic system-associated membrane protein
chr6_-_49712055 1.030 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr16_-_31147062 1.017 NM_002773
PRSS8
protease, serine, 8
chr15_+_41056243 1.016 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr13_-_110802708 1.016 COL4A1
collagen, type IV, alpha 1
chr2_-_188419185 1.010 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr3_-_149095517 0.995 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr6_+_131958441 0.995 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_-_25706177 0.994 NM_152590
NM_001145728
NM_001145729
IFLTD1


intermediate filament tail domain containing 1


chr12_-_102872329 0.986 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr4_-_38858407 0.986 NM_006068
TLR6
toll-like receptor 6
chr11_-_85430117 0.979 NM_206929
SYTL2
synaptotagmin-like 2
chr11_-_8832881 0.971 NM_139157
ST5
suppression of tumorigenicity 5
chrX_+_123480131 0.966 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr12_+_69742130 0.955 NM_000239
LYZ
lysozyme
chr14_+_29236882 0.947 FOXG1
forkhead box G1
chr22_+_51176623 0.946 NM_001097
ACR
acrosin
chr14_-_106237675 0.946 IGHM
immunoglobulin heavy constant mu
chr5_+_140201221 0.929 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr1_+_26485510 0.920 NM_024869
FAM110D
family with sequence similarity 110, member D
chr1_-_168698412 0.920 NM_001937
DPT
dermatopontin
chr1_+_16767166 0.918 NM_001145277
NM_001145278
NM_018090
NECAP2


NECAP endocytosis associated 2


chr11_+_66790815 0.906 NM_177963
SYT12
synaptotagmin XII
chr17_-_41836132 0.899 NM_025237
SOST
sclerostin
chr11_+_111385509 0.898 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr2_-_158300517 0.897 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_-_159825136 0.893 NM_001134233
C1orf204
chromosome 1 open reading frame 204
chr1_+_16767218 0.885 NECAP2
NECAP endocytosis associated 2
chr3_+_149192367 0.867 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr6_-_138820578 0.861 NM_001144060
NHSL1
NHS-like 1
chr6_-_133035180 0.860 NM_004666
VNN1
vanin 1
chr9_+_116918230 0.856 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr14_-_106111114 0.853 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr2_-_161056762 0.846 ITGB6
integrin, beta 6
chr9_+_140145712 0.846 NM_001004353
C9orf173
chromosome 9 open reading frame 173
chr11_+_6226797 0.840 NM_173525
C11orf42
chromosome 11 open reading frame 42
chr14_-_106641585 0.836 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_43031343 0.829 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr2_+_234601511 0.825 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr5_+_140213968 0.818 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr14_+_100531745 0.808 NM_016337
EVL
Enah/Vasp-like
chr19_+_7953380 0.795 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr16_+_82068830 0.795 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_111789600 0.794 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr11_+_111789658 0.778 C11orf52
chromosome 11 open reading frame 52
chr2_-_230933618 0.778 NM_152527
SLC16A14
solute carrier family 16, member 14 (monocarboxylic acid transporter 14)
chr9_+_112403067 0.776 NM_001037293
PALM2
paralemmin 2
chr4_-_184243578 0.775 NM_001185149
CLDN24
claudin 24
chr11_+_125616187 0.774 NM_138294
PATE1
prostate and testis expressed 1
chr1_-_110933683 0.769 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr9_-_14086901 0.768 NFIB
nuclear factor I/B
chr17_+_26646120 0.754 NM_014573
TMEM97
transmembrane protein 97
chr1_+_27719151 0.746 NM_005281
GPR3
G protein-coupled receptor 3
chr19_-_14952688 0.742 NM_001005190
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr6_+_30908776 0.741 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr2_-_216289936 0.739 FN1
fibronectin 1
chr1_+_198608216 0.735 PTPRC
protein tyrosine phosphatase, receptor type, C
chr16_-_15833937 0.734 MYH11
myosin, heavy chain 11, smooth muscle
chr12_+_69742140 0.730 LYZ
lysozyme
chr12_-_68619535 0.730 NM_018402
IL26
interleukin 26
chr2_+_102979096 0.728 NM_003855
IL18R1
interleukin 18 receptor 1
chr17_-_46507481 0.722 NM_001075099
NM_003726
SKAP1

src kinase associated phosphoprotein 1

chr11_-_114430579 0.719 NM_152315
FAM55A
family with sequence similarity 55, member A
chr12_+_54378929 0.719 NM_017409
HOXC10
homeobox C10
chr14_-_106994001 0.714 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr8_+_11351509 0.713 NM_001715
BLK
B lymphoid tyrosine kinase
chr17_-_53800074 0.709 NM_018286
TMEM100
transmembrane protein 100
chr5_+_140180782 0.708 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr22_+_39916563 0.704 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr16_-_31146992 0.704 PRSS8
protease, serine, 8
chr5_-_87969135 0.703 LINC00461
long intergenic non-protein coding RNA 461
chr1_-_24239758 0.694 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr1_-_1356823 0.694 NM_001145210
NM_001243535
NM_001243536
ANKRD65


ankyrin repeat domain 65


chr21_-_43816123 0.693 NM_024022
NM_032405
TMPRSS3

transmembrane protease, serine 3


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
10.69 1.12e-04 GO:0006805 xenobiotic metabolic process
10.69 1.12e-04 GO:0071466 cellular response to xenobiotic stimulus
10.61 1.20e-04 GO:0009410 response to xenobiotic stimulus
7.22 8.68e-04 GO:0008202 steroid metabolic process
1.67 1.28e-03 GO:0050896 response to stimulus
2.41 1.31e-03 GO:0042221 response to chemical stimulus
3.84 2.24e-02 GO:0042060 wound healing
157.83 2.74e-02 GO:0001915 negative regulation of T cell mediated cytotoxicity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.99 6.92e-08 GO:0005576 extracellular region
6.13 6.86e-06 GO:0031012 extracellular matrix
6.20 5.70e-05 GO:0005578 proteinaceous extracellular matrix
3.27 2.58e-04 GO:0044421 extracellular region part
5.20 3.60e-04 GO:0009986 cell surface
8.01 2.96e-03 GO:0009897 external side of plasma membrane
2.18 5.16e-03 GO:0044459 plasma membrane part
19.74 4.92e-02 GO:0034364 high-density lipoprotein particle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
10.33 8.46e-04 GO:0019838 growth factor binding
67.65 1.39e-03 GO:0031210 phosphatidylcholine binding
17.55 1.51e-03 GO:0019825 oxygen binding
4.55 2.10e-03 GO:0008289 lipid binding
10.89 3.04e-03 GO:0004867 serine-type endopeptidase inhibitor activity
14.10 4.48e-03 GO:0004896 cytokine receptor activity
14.10 4.48e-03 GO:0033293 monocarboxylic acid binding
47.36 4.71e-03 GO:0050997 quaternary ammonium group binding
157.83 6.53e-03 GO:0018675 (S)-limonene 6-monooxygenase activity
157.83 6.53e-03 GO:0018676 (S)-limonene 7-monooxygenase activity
157.83 6.53e-03 GO:0019113 limonene monooxygenase activity
157.83 6.53e-03 GO:0033767 4-hydroxyacetophenone monooxygenase activity
7.42 7.32e-03 GO:0031406 carboxylic acid binding
5.23 9.35e-03 GO:0004857 enzyme inhibitor activity
8.78 1.04e-02 GO:0019955 cytokine binding
17.07 1.40e-02 GO:0005504 fatty acid binding
4.33 1.74e-02 GO:0030246 carbohydrate binding
29.60 2.14e-02 GO:0008395 steroid hydroxylase activity